Rolf Müller Selected Research

soraphen A

8/2023	Modulation of cytokine release from peripheral blood mononuclear cells from multiple sclerosis patients by coenzyme A and soraphen A.
10/2021	Physiologically Based Pharmacokinetic/Pharmacodynamic Model for the Treatment of Dengue Infections Applied to the Broad Spectrum Antiviral Soraphen A.
1/2021	Targeting cellular fatty acid synthesis limits T helper and innate lymphoid cell function during intestinal inflammation and infection.
1/2019	ACC1 (Acetyl Coenzyme A Carboxylase 1) Is a Potential Immune Modulatory Target of Cerebral Ischemic Stroke.
1/2018	Targeting de novo lipogenesis as a novel approach in anti-cancer therapy.
3/2015	Soraphen A: A Probe for Investigating the Role of de Novo Lipogenesis during Viral Infection.
11/2014	De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Rolf Müller Research Topics

Disease

83	Neoplasms (Cancer) 01/2024 - 02/2002
32	Infections 12/2023 - 06/2012
14	Ovarian Neoplasms (Ovarian Cancer) 01/2023 - 05/2015
12	Carcinoma (Carcinomatosis) 01/2022 - 12/2003
11	Ascites 01/2023 - 01/2014
10	Inflammation (Inflammations) 01/2024 - 01/2008
10	Carcinogenesis 01/2024 - 01/2006
10	Neoplasm Metastasis (Metastasis) 01/2023 - 11/2012
8	Tuberculosis (Tuberculoses) 01/2024 - 04/2010
7	Dehydration (Water Stress) 01/2022 - 02/2005
4	Bacterial Infections (Bacterial Infection) 07/2023 - 01/2018
4	Melanoma (Melanoma, Malignant) 01/2019 - 02/2002
3	Communicable Diseases (Infectious Diseases) 02/2024 - 01/2016
3	Hepatocellular Carcinoma (Hepatoma) 11/2019 - 05/2003
3	Fatty Liver 01/2016 - 12/2014
2	Staphylococcal Infections 02/2024 - 08/2023
2	Malaria 02/2024 - 09/2023
2	Disease Progression 01/2024 - 01/2016
2	Choroidal Neovascularization 08/2022 - 12/2021
2	Autoimmune Diseases (Autoimmune Disease) 12/2021 - 11/2014
2	Dengue (Dengue Fever) 10/2021 - 04/2015
2	Colitis 01/2021 - 01/2018
2	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2020 - 01/2017
2	Neurodegenerative Diseases (Neurodegenerative Disease) 06/2019 - 01/2017
2	Dementia (Dementias) 01/2018 - 12/2016
2	Prostatic Neoplasms (Prostate Cancer) 11/2017 - 01/2005
2	Breast Neoplasms (Breast Cancer) 04/2014 - 11/2012
1	COVID-19 02/2024

Drug/Important Bio-Agent (IBA)

23	Anti-Bacterial Agents (Antibiotics)IBA 01/2024 - 11/2008
16	Proteins (Proteins, Gene)FDA Link 12/2023 - 05/2006
13	Adenosine Triphosphatases (ATPase)IBA 01/2022 - 11/2012
11	LipidsIBA 12/2022 - 01/2008
10	EnzymesIBA 12/2022 - 04/2009
9	LigandsIBA 12/2022 - 02/2002
9	Peptides (Polypeptides)IBA 01/2020 - 02/2002
9	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2017 - 01/2006
7	soraphen AIBA 08/2023 - 11/2014
6	CytokinesIBA 01/2024 - 01/2014
6	DNA (Deoxyribonucleic Acid)IBA 01/2019 - 05/2006
5	Acetyl-CoA CarboxylaseIBA 08/2023 - 01/2018
5	Fatty Acids (Saturated Fatty Acids)IBA 01/2021 - 05/2015
5	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 11/2015 - 01/2006
5	PPAR-betaIBA 01/2008 - 01/2006
4	Interleukin-6 (Interleukin 6)IBA 01/2024 - 01/2014
3	Virulence Factors (Pathogenicity Factors)IBA 12/2023 - 01/2018
3	VaccinesIBA 09/2023 - 04/2015
3	Antiviral Agents (Antivirals)IBA 01/2023 - 01/2019
3	TubulinIBA 01/2023 - 01/2012
3	Conditioned Culture MediaIBA 12/2022 - 01/2019
3	corallopyronin AIBA 01/2022 - 01/2019
3	PolyketidesIBA 01/2021 - 06/2012
3	colibactinIBA 01/2020 - 05/2015
3	Glucose (Dextrose)FDA LinkGeneric 11/2019 - 01/2008
3	Adenosine Triphosphate (ATP)IBA 11/2019 - 11/2012
3	Messenger RNA (mRNA)IBA 11/2019 - 08/2007
3	Interleukin-10 (Interleukin 10)IBA 01/2018 - 01/2014
3	IntegrinsIBA 01/2018 - 05/2004
3	carolactonIBA 11/2017 - 11/2016
3	CholesterolIBA 02/2017 - 12/2014
3	Proton Pumps (Proton Pump)IBA 01/2016 - 11/2012
2	sorangicin AIBA 02/2024 - 08/2023
2	chelocardin (cetocycline)IBA 12/2023 - 12/2020
2	chlorotonil AIBA 10/2023 - 11/2014
2	Coenzyme A (CoA)IBA 08/2023 - 01/2016
2	lysophosphatidic acidIBA 01/2023 - 01/2019
2	Arachidonic Acid (Vitamin F)IBA 01/2022 - 01/2021
2	Rifampin (Rifampicin)FDA LinkGeneric 01/2022 - 12/2020
2	17-hydroxyestrane-3-carbonitrile (ECN)IBA 11/2021 - 03/2019
2	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 01/2021 - 05/2015
2	Small Interfering RNA (siRNA)IBA 01/2020 - 10/2009
2	Vacuolar Proton-Translocating ATPases (V-Type ATPase)IBA 11/2019 - 04/2014
2	Carrier Proteins (Binding Protein)IBA 11/2019 - 12/2014
2	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2019 - 05/2004
2	RNA (Ribonucleic Acid)IBA 01/2019 - 02/2002
2	Interleukin-12 (IL 12)IBA 01/2018 - 01/2017
2	Paclitaxel (Taxol)FDA LinkGeneric 01/2018 - 06/2005
2	LipopeptidesIBA 01/2018 - 05/2004
2	Phospholipids (Phosphatides)FDA LinkGeneric 01/2018 - 01/2016
2	Transcription Factors (Transcription Factor)IBA 01/2018 - 01/2008
2	archazolid AIBA 01/2018 - 11/2017
2	ChromatinIBA 01/2018 - 01/2018
2	Protons (Proton)IBA 01/2017 - 10/2014
2	AntigensIBA 01/2017 - 05/2006
2	Proton-Translocating ATPases (ATPase, H+)IBA 01/2017 - 10/2014
2	AcidsIBA 01/2016 - 08/2013
2	Insulin-Like PeptidesIBA 01/2016 - 12/2014
2	Epothilones (Epothilone)IBA 11/2014 - 11/2007
2	MacrolidesIBA 10/2014 - 04/2010
2	pretubulysinIBA 03/2014 - 01/2012
2	ErbB Receptors (EGF Receptor)IBA 11/2012 - 04/2003
2	Liposomes (Liposome)IBA 05/2006 - 05/2004
2	Monophenol Monooxygenase (Tyrosinase)IBA 05/2006 - 02/2002
2	cyclic arginine-glycine-aspartic acid peptideIBA 05/2004 - 02/2002
2	Epidermal Growth Factor (EGF)IBA 12/2003 - 04/2003
2	Antisense OligonucleotidesIBA 04/2003 - 02/2002
1	Antiparasitic Agents (Antiparasitics)IBA 02/2024

Therapy/Procedure

35	Therapeutics 08/2023 - 03/2004
5	Drug Therapy (Chemotherapy) 09/2023 - 01/2016
2	Drug Administration Routes 02/2024 - 08/2023
2	Lasers (Laser) 08/2022 - 12/2021